Does the combo bag/seat need to be removed to fold it properly?
If I understand you correctly, you're asking if the chassis can be folded with the 2in1 combination of the bassinet-seat part. If that is so, the answer is no, unfortunately. If using the carrycot-seat unit 2in1 part, you need to remove that part first and then fold the frame.
The pushchair's frame only folds with the world-facing seat.